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Magnesium Citrate vs Magnesium Glycinate

Compare Magnesium Citrate and Magnesium Glycinate: timing, food, doses, forms and existing interaction guidance.

Magnesium Citrate vs Magnesium Glycinate
Magnesium CitrateMagnesium Glycinate
CategoryMineralsMinerals
Best timeBreakfast / DinnerBedtime
FoodWith or without foodWith or without food
Common dose100–350 mg100–350 mg
Upper limit
350 mg/day

UL applies to all supplemental magnesium combined (not food); mainly to prevent diarrhea.

350 mg/day

UL applies to all supplemental magnesium combined (not food); mainly to prevent diarrhea.

SolubilityWater-solubleWater-soluble
DescriptionOne of the better-absorbed, inexpensive forms: in a randomized comparison it raised magnesium levels more than amino-acid chelate or oxide. Its laxative effect is useful for constipation but limits the dose some people tolerate.Magnesium bound to the amino acid glycine. Popular for sleep and generally well tolerated, with less laxative effect than citrate or oxide. Trials of this specific form are scarce — the sleep reputation is extrapolated from magnesium and glycine separately.
Timing noteAny time of day, with a glass of water. Larger doses loosen stools — it's also sold as a laxative.Usually taken in the evening or at bedtime; it's gentle on the stomach, so food is optional.
Forms to look for
  • Capsules or powder dosed in elemental magnesium
  • Split the dose if it upsets your stomach
  • Check elemental magnesium per serving — glycinate is only about 14% magnesium by weight
  • Fully reacted (buffered products may contain oxide)
References
  1. 01NIH Office of Dietary Supplements — Magnesium Fact Sheet for Health Professionals
  2. 02Walker AF et al. Mg citrate found more bioavailable than other Mg preparations in a randomised, double-blind study. Magnes Res 2003.
  1. 01NIH Office of Dietary Supplements — Magnesium Fact Sheet for Health Professionals
  2. 02Bannai M et al. The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. Front Neurol 2012.

Common product or study range — not a personal recommendation. Upper limits are ceilings, not targets.

If you take both

NoteStrong evidence

Usually unnecessary — both supply magnesium, and the amounts add up.

Pick one form, or add up the elemental magnesium on both labels.

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Common questions

What is the difference between Magnesium Citrate and Magnesium Glycinate?

Magnesium Citrate: One of the better-absorbed, inexpensive forms: in a randomized comparison it raised magnesium levels more than amino-acid chelate or oxide. Its laxative effect is useful for constipation but limits the dose some people tolerate. Magnesium Glycinate: Magnesium bound to the amino acid glycine. Popular for sleep and generally well tolerated, with less laxative effect than citrate or oxide. Trials of this specific form are scarce — the sleep reputation is extrapolated from magnesium and glycine separately.

Can I take Magnesium Citrate and Magnesium Glycinate together?

Usually unnecessary — both supply magnesium, and the amounts add up.

Last reviewed Sourced from NIH fact sheets and peer-reviewed studies.How we make this contentReport an error