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Medications

Supplements and GLP-1 medication

semaglutide (Ozempic, Wegovy, Rybelsus), tirzepatide (Mounjaro, Zepbound), liraglutide

Note

BerberineNoteMechanism-based

Berberine with GLP-1 drugs: blood sugar and stomach upset add up. Both lower blood sugar and commonly cause nausea or diarrhea. GLP-1 drugs also slow stomach emptying, which can change how other oral products are absorbed. Tell your prescriber.

  1. 01Ozempic / Rybelsus U.S. prescribing information — delayed gastric emptying and other oral drugs
  2. 02Lan J et al. Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension. J Ethnopharmacol 2015.
Check your stack with GLP-1 medication

Common questions

Can I take Berberine with GLP-1 medication?

Berberine with GLP-1 drugs: blood sugar and stomach upset add up. Both lower blood sugar and commonly cause nausea or diarrhea. GLP-1 drugs also slow stomach emptying, which can change how other oral products are absorbed. Tell your prescriber.

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