Adaptogens

Lion's Mane — timing, dose & interactions

Medicinal mushroom that stimulates nerve growth factor in lab studies. One small trial showed cognitive benefit in mild cognitive impairment that faded after stopping.

Also known as Hericium erinaceus

Timing

When to take it

Any time; morning is common.

Interactions

Lion's Mane with other supplements

No documented supplement interactions in our dataset.

Safety

Medications & health conditions

CautionPregnant or breastfeeding

Lion's mane: no safety data in pregnancy. Lion's mane has not been studied for safety in pregnancy or breastfeeding. Avoid unless your clinician recommends it.

Mechanism-based

Buying guide

What to look for on the label

  • Lion's Mane

    • Fruiting-body extract (not mycelium on grain)
    • Beta-glucan content stated on label

FAQ

Common questions

When is the best time to take Lion's Mane?

Breakfast or Lunch. Any time; morning is common.

Should Lion's Mane be taken with food?

It can be taken with or without food. Any time; morning is common.

Sources

References

  1. 01Mori K et al. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res 2009.