Medications
Supplements and Erectile dysfunction medication
sildenafil (Viagra), tadalafil (Cialis), vardenafil
Note
Arginine and ED pills both lower blood pressure. Arginine raises nitric oxide, and PDE5 inhibitors amplify its effect. They haven't been studied together; watch for dizziness.
- 01Dong JY et al. Effect of oral L-arginine supplementation on blood pressure: a meta-analysis of randomized, double-blind, placebo-controlled trials. Am Heart J 2011.
- 02No direct human interaction studies found in PubMed (searched 2026-09-30) — theoretical, based on mechanism
Citrulline and ED pills both lower blood pressure. Citrulline raises nitric oxide, and PDE5 inhibitors amplify its effect. They haven't been studied together; watch for dizziness.
- 01Schwedhelm E et al. Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. Br J Clin Pharmacol 2008.
- 02No direct human interaction studies found in PubMed (searched 2026-09-30) — theoretical, based on mechanism
Common questions
Can I take L-Arginine with Erectile dysfunction medication?
Arginine and ED pills both lower blood pressure. Arginine raises nitric oxide, and PDE5 inhibitors amplify its effect. They haven't been studied together; watch for dizziness.
Can I take L-Citrulline with Erectile dysfunction medication?
Citrulline and ED pills both lower blood pressure. Citrulline raises nitric oxide, and PDE5 inhibitors amplify its effect. They haven't been studied together; watch for dizziness.