Vitamins

Folate — timing, dose & interactions

Required for DNA synthesis and methylation, and critical before and during early pregnancy to prevent neural tube defects.

Also known as Folic acid, Methylfolate, 5-MTHF, Vitamin B9

Timing

When to take it

Any time; often taken with other B vitamins in the morning.

Dose note. Adult UL applies to folic acid from supplements and fortified foods (not food folate).

Interactions

Folate with other supplements

Buying guide

What to look for on the label

  • Folate

    • Methylfolate (5-MTHF) or folic acid
    • Pair with B12 — high folate can mask B12 deficiency

FAQ

Common questions

When is the best time to take Folate?

Breakfast. Any time; often taken with other B vitamins in the morning.

Should Folate be taken with food?

It can be taken with or without food. Any time; often taken with other B vitamins in the morning.

Can you take Folate with Vitamin B12?

Yes — and if you take folate, you should make sure your B12 is adequate. Take them together, or at least check your B12 status if you supplement folate.

Sources

References

  1. 01NIH Office of Dietary Supplements — Folate Fact Sheet for Health Professionals