Longevity
Spermidine — timing, dose & interactions
Polyamine (wheat germ, aged cheese, mushrooms) that induces autophagy and extends lifespan in animals. A 12-month human trial found no memory benefit.
Timing
When to take it
Take with breakfast.
Interactions
Spermidine with other supplements
No documented supplement interactions in our dataset.
Safety
Medications & health conditions
CautionPregnant or breastfeeding
Spermidine: no safety data in pregnancy. Spermidine has not been studied for safety in pregnancy or breastfeeding. Avoid unless your clinician recommends it.
Mechanism-based
Buying guide
What to look for on the label
Spermidine
- Wheat-germ extract standardized for spermidine
FAQ
Common questions
When is the best time to take Spermidine?
Breakfast. Take with breakfast.
Should Spermidine be taken with food?
Yes. Taking it with a meal reduces stomach upset.
Sources