Vitamins
Vitamin B12 — timing, dose & interactions
Needed for red blood cells, nerve myelin and DNA synthesis. Deficiency is common in vegans, older adults, and people on metformin or acid-reducing drugs.
Also known as Cobalamin, Methylcobalamin, Cyanocobalamin
Timing
When to take it
Morning is typical. Absorption per dose is limited, so higher oral doses make up for it.
Dose note. No UL established.
Interactions
Vitamin B12 with other supplements
Buying guide
What to look for on the label
Vitamin B12
- Methylcobalamin or cyanocobalamin (both effective)
- Sublingual forms are not required
FAQ
Common questions
When is the best time to take Vitamin B12?
Breakfast. Morning is typical. Absorption per dose is limited, so higher oral doses make up for it.
Should Vitamin B12 be taken with food?
It can be taken with or without food. Morning is typical. Absorption per dose is limited, so higher oral doses make up for it.
Can you take Vitamin B12 with Folate?
Yes — and if you take folate, you should make sure your B12 is adequate. Take them together, or at least check your B12 status if you supplement folate.
Sources