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Melatonin + Valerian

Can you take Melatonin and Valerian together?

NoteMechanism-based

Usually fine, but the drowsiness may add up — start low.

What to do. Try one at a time first. Don't drive or drink alcohol after taking them.

Mechanism

Two sleep aids together

Both are taken to promote sleep. They haven't been studied together, and NIH advises against combining valerian with other sedatives.

Evidence: Mechanism-based — Plausible biological mechanism with little direct human outcome data.

  1. 01NIH NCCIH — Valerian
  2. 02NIH NCCIH — Melatonin: What You Need To Know

Timing

A day with Melatonin and Valerian

  1. 22:30

    Bedtime

    no food

Taking more than these two?

Add the rest of your stack and your medications for a complete check.

Check my full stack

Buying guide

What to look for on the label

  • Melatonin

    • Low-dose tablets (0.3–1 mg)
    • Third-party tested — product content varies widely

  • Valerian

    • Valerian root extract standardized for valerenic acid

Learn more about Melatonin and Valerian

Last reviewed Sourced from NIH fact sheets and peer-reviewed studies.How we make this contentReport an error