Omega-3 (Fish Oil) + Vitamin D3
Can you take Omega-3 (Fish Oil) and Vitamin D3 together?
Yes — taking D3 with fat (including a fish-oil meal) helps absorption.
What to do. Take both with the same meal that contains some fat.
Mechanism
Dietary fat improves vitamin D3 absorption
Vitamin D3 is absorbed with dietary fat via micelles. In a controlled study, taking D3 with a fat-containing meal raised blood levels ~32% more than a fat-free meal.
Evidence: Human data — Human pharmacokinetic, cohort or case-series data.
Timing
A day with Omega-3 (Fish Oil) and Vitamin D3
- 12:30
Lunch
with meal
Taking more than these two?
Add the rest of your stack and your medications for a complete check.
Buying guide
What to look for on the label
Omega-3 (Fish Oil)
- Triglyceride (rTG) form
- Third-party tested for oxidation and heavy metals (e.g. IFOS)
- Algae oil for a vegan option
Vitamin D3
- D3 (cholecalciferol) rather than D2
- Oil-based softgels
Related
Other interactions
Omega-3 (Fish Oil) + Vitamin K2
Fat-soluble K2 absorbs better with fat
Omega-3 (Fish Oil) + Vitamin A
Fat-soluble vitamin A absorbs better with fat
CoQ10 + Omega-3 (Fish Oil)
CoQ10 absorbs better with fat
Omega-3 (Fish Oil) + Vitamin E
Vitamin E protects omega-3s from oxidation
Astaxanthin + Omega-3 (Fish Oil)
Fat-soluble astaxanthin absorbs with fish oil
Vitamin D3 + Vitamin K2
D3 makes calcium-binding proteins; K2 activates them
Learn more about Omega-3 (Fish Oil) and Vitamin D3.