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Medications

Supplements and Tetracycline or quinolone antibiotics

doxycycline, minocycline, ciprofloxacin, levofloxacin

Caution

Multivitamin/mineralCautionMechanism-based

Minerals in multivitamins can block these antibiotics. Calcium, iron, magnesium and zinc in multivitamins bind tetracycline and quinolone antibiotics. Space them as the antibiotic's label advises.

CalciumCautionStrong evidence

Calcium blocks absorption of these antibiotics. Calcium binds tetracycline and quinolone antibiotics in the gut, which can make the antibiotic less effective. Typically take the antibiotic at least 2 hours before or 4–6 hours after calcium — the exact spacing depends on the drug, so follow its label.

IronCautionStrong evidence

Iron blocks absorption of these antibiotics. Iron binds tetracycline and quinolone antibiotics in the gut, which can make the antibiotic less effective. Typically take the antibiotic at least 2 hours before or 4–6 hours after iron — the exact spacing depends on the drug, so follow its label.

MagnesiumCautionStrong evidence

Magnesium blocks absorption of these antibiotics. Magnesium binds tetracycline and quinolone antibiotics in the gut, which can make the antibiotic less effective. Typically take the antibiotic at least 2 hours before or 4–6 hours after magnesium — the exact spacing depends on the drug, so follow its label.

ZincCautionStrong evidence

Zinc blocks absorption of these antibiotics. Zinc binds tetracycline and quinolone antibiotics in the gut, which can make the antibiotic less effective. Typically take the antibiotic at least 2 hours before or 4–6 hours after zinc — the exact spacing depends on the drug, so follow its label.

Ca-AKGCautionStrong evidence

The calcium in Ca-AKG blocks absorption of these antibiotics. Calcium binds tetracycline and quinolone antibiotics in the gut, which can make the antibiotic less effective. Typically take the antibiotic at least 2 hours before or 4–6 hours after Ca-AKG — follow the drug's label.

Note

ProbioticsNoteHuman data

Space probiotics from antibiotics. Take probiotics at least 2 hours after the antibiotic so fewer organisms are killed.

Check your stack with Tetracycline or quinolone antibiotics

Common questions

Can I take Multivitamin/mineral with Tetracycline or quinolone antibiotics?

Minerals in multivitamins can block these antibiotics. Calcium, iron, magnesium and zinc in multivitamins bind tetracycline and quinolone antibiotics. Space them as the antibiotic's label advises.

Can I take Calcium with Tetracycline or quinolone antibiotics?

Calcium blocks absorption of these antibiotics. Calcium binds tetracycline and quinolone antibiotics in the gut, which can make the antibiotic less effective. Typically take the antibiotic at least 2 hours before or 4–6 hours after calcium — the exact spacing depends on the drug, so follow its label.

Can I take Iron with Tetracycline or quinolone antibiotics?

Iron blocks absorption of these antibiotics. Iron binds tetracycline and quinolone antibiotics in the gut, which can make the antibiotic less effective. Typically take the antibiotic at least 2 hours before or 4–6 hours after iron — the exact spacing depends on the drug, so follow its label.

Can I take Magnesium with Tetracycline or quinolone antibiotics?

Magnesium blocks absorption of these antibiotics. Magnesium binds tetracycline and quinolone antibiotics in the gut, which can make the antibiotic less effective. Typically take the antibiotic at least 2 hours before or 4–6 hours after magnesium — the exact spacing depends on the drug, so follow its label.

Can I take Zinc with Tetracycline or quinolone antibiotics?

Zinc blocks absorption of these antibiotics. Zinc binds tetracycline and quinolone antibiotics in the gut, which can make the antibiotic less effective. Typically take the antibiotic at least 2 hours before or 4–6 hours after zinc — the exact spacing depends on the drug, so follow its label.

Can I take Ca-AKG with Tetracycline or quinolone antibiotics?

The calcium in Ca-AKG blocks absorption of these antibiotics. Calcium binds tetracycline and quinolone antibiotics in the gut, which can make the antibiotic less effective. Typically take the antibiotic at least 2 hours before or 4–6 hours after Ca-AKG — follow the drug's label.

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