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Vitamins

Multivitamin/mineral — timing, dose & interactions

Combines vitamins and minerals in one product. Formulas differ a lot, so the label decides what it adds to the rest of your stack — common overlaps are vitamin D, B vitamins, zinc, iron, calcium and vitamin K.

Also known as: Multivitamin, MVM, Multi, Centrum, One A Day

Timing

When to take it

Take with a meal; contents vary widely, so check the label.

Interactions

Multivitamin/mineral with other supplements

No documented supplement interactions in our dataset.

Safety

Medications & health conditions

CautionWarfarin

Multivitamins may contain vitamin K. NIH advises people on warfarin to talk with their health care provider before taking any multivitamin that contains vitamin K, because vitamin K lowers warfarin's effect. Keep your intake consistent and check the label.

Strong evidence

Multivitamins with calcium or iron can reduce levothyroxine absorption. If your multivitamin contains calcium, iron or magnesium, keep it at least 4 hours from your thyroid medication, as for those minerals on their own.

Mechanism-based

Minerals in multivitamins can block these antibiotics. Calcium, iron, magnesium and zinc in multivitamins bind tetracycline and quinolone antibiotics. Space them as the antibiotic's label advises.

Mechanism-based

Multivitamins with calcium or iron block HIV integrase inhibitors. The dolutegravir label names multivitamins containing calcium or iron: take them together with a meal, or take the HIV medicine 2 hours before or 6 hours after.

Strong evidence

Biotin in multivitamins can affect lab tests. Many multivitamins contain biotin, which can distort some blood tests such as thyroid tests. Tell whoever orders your test.

Mechanism-based

Buying guide

What to look for on the label

Quality seals: supplements don't need FDA approval before sale. Seals from USP, NSF or ConsumerLab show a product was tested for what's on the label and for contaminants — they don't guarantee it's safe or effective. NIH ODS: Dietary Supplements — What You Need to Know

  • Multivitamin/mineral

    • Check the label for vitamin K, iron, calcium, biotin and zinc amounts
    • Third-party tested (USP, NSF or ConsumerLab)

FAQ

Common questions

When is the best time to take Multivitamin/mineral?

Breakfast. Take with a meal; contents vary widely, so check the label.

Should Multivitamin/mineral be taken with food?

Yes. Taking it with a meal reduces stomach upset.

Sources

References

  1. 01NIH Office of Dietary Supplements — Multivitamin/mineral Supplements Fact Sheet for Health Professionals
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