Medications
Supplements and HIV integrase inhibitors
dolutegravir (Tivicay, Triumeq, Dovato), bictegravir (Biktarvy)
Critical
St. John's wort can make HIV treatment fail. It lowers dolutegravir and bictegravir levels; the labels say to avoid the combination.
Caution
Multivitamins with calcium or iron block HIV integrase inhibitors. The dolutegravir label names multivitamins containing calcium or iron: take them together with a meal, or take the HIV medicine 2 hours before or 6 hours after.
Calcium and iron block HIV integrase inhibitors. They bind dolutegravir and bictegravir in the gut and lower their levels. Take them together with a meal, or take the HIV medicine 2 hours before or 6 hours after the supplement, per its label.
Calcium and iron block HIV integrase inhibitors. They bind dolutegravir and bictegravir in the gut and lower their levels. Take them together with a meal, or take the HIV medicine 2 hours before or 6 hours after the supplement, per its label.
Calcium and iron block HIV integrase inhibitors. They bind dolutegravir and bictegravir in the gut and lower their levels. Take them together with a meal, or take the HIV medicine 2 hours before or 6 hours after the supplement, per its label.
Magnesium blocks HIV integrase inhibitors. The labels advise taking dolutegravir or bictegravir 2 hours before or 6 hours after products containing magnesium.
Zinc may block HIV integrase inhibitors. Like calcium, iron and magnesium, zinc is a polyvalent mineral that these drugs can bind. Space them as you would calcium or iron.
Common questions
Can I take St. John's Wort with HIV integrase inhibitors?
St. John's wort can make HIV treatment fail. It lowers dolutegravir and bictegravir levels; the labels say to avoid the combination.
Can I take Multivitamin/mineral with HIV integrase inhibitors?
Multivitamins with calcium or iron block HIV integrase inhibitors. The dolutegravir label names multivitamins containing calcium or iron: take them together with a meal, or take the HIV medicine 2 hours before or 6 hours after.
Can I take Calcium with HIV integrase inhibitors?
Calcium and iron block HIV integrase inhibitors. They bind dolutegravir and bictegravir in the gut and lower their levels. Take them together with a meal, or take the HIV medicine 2 hours before or 6 hours after the supplement, per its label.
Can I take Iron with HIV integrase inhibitors?
Calcium and iron block HIV integrase inhibitors. They bind dolutegravir and bictegravir in the gut and lower their levels. Take them together with a meal, or take the HIV medicine 2 hours before or 6 hours after the supplement, per its label.
Can I take Ca-AKG with HIV integrase inhibitors?
Calcium and iron block HIV integrase inhibitors. They bind dolutegravir and bictegravir in the gut and lower their levels. Take them together with a meal, or take the HIV medicine 2 hours before or 6 hours after the supplement, per its label.
Can I take Magnesium with HIV integrase inhibitors?
Magnesium blocks HIV integrase inhibitors. The labels advise taking dolutegravir or bictegravir 2 hours before or 6 hours after products containing magnesium.