Longevity
Apigenin — timing, dose & interactions
Flavonoid in chamomile, parsley and celery. It is popular for sleep and, based on lab and mouse studies, as a CD38 inhibitor that may preserve NAD⁺. Human evidence for apigenin supplements themselves is very limited.
Timing
When to take it
Usually taken 30–60 minutes before bed.
Interactions
Apigenin with other supplements
No documented supplement interactions in our dataset.
Safety
Medications & health conditions
Apigenin may add to sedation. Apigenin is the flavonoid behind chamomile's calming reputation, and NIH notes theoretical reasons chamomile might interact with sedatives. Start low and avoid driving until you know how the combination affects you.
Apigenin: no safety data in pregnancy. Apigenin has not been studied for safety in pregnancy or breastfeeding. Avoid unless your clinician recommends it.
Buying guide
What to look for on the label
Apigenin
- Apigenin 50 mg capsules
- Chamomile extract standardized for apigenin
FAQ
Common questions
When is the best time to take Apigenin?
Bedtime. Usually taken 30–60 minutes before bed.
Should Apigenin be taken with food?
It can be taken with or without food. Usually taken 30–60 minutes before bed.
Sources