Longevity
Pterostilbene — timing, dose & interactions
Close chemical relative of resveratrol, found in blueberries. In a randomized trial, 125 mg twice daily lowered blood pressure but, taken alone, raised LDL cholesterol. It was well tolerated at up to 250 mg/day.
Timing
When to take it
Take with a meal.
Interactions
Pterostilbene with other supplements
Safety
Medications & health conditions
Pterostilbene may raise LDL cholesterol. In a randomized trial, pterostilbene alone raised LDL by about 17 mg/dL; the rise was smaller in people already on cholesterol medication. Recheck your lipids after starting.
Antioxidants may interfere with cancer treatment. Some chemotherapy and radiation work partly through oxidative damage; high-dose antioxidants could reduce their effect. Discuss every supplement with your oncology team.
Pterostilbene: no safety data in pregnancy. Pterostilbene has not been studied for safety in pregnancy or breastfeeding. Avoid unless your clinician recommends it.
Buying guide
What to look for on the label
Pterostilbene
- trans-Pterostilbene
- If you track LDL cholesterol, recheck it after starting
FAQ
Common questions
When is the best time to take Pterostilbene?
Breakfast / Lunch. Take with a meal.
Should Pterostilbene be taken with food?
Yes. It is fat-soluble, so take it with a meal that contains some fat.
Can you take Pterostilbene with Resveratrol?
No need to take both — they're chemically similar, and the pair hasn't been studied. Pick one. If you choose pterostilbene and track your cholesterol, recheck LDL after a couple of months.
Sources