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Medications

Supplements and Diabetes medication

metformin, insulin, sulfonylureas

Caution

AshwagandhaCautionHuman data

Ashwagandha may lower blood sugar. Additive glucose-lowering could increase hypoglycemia risk with insulin or sulfonylureas. Monitor glucose.

BerberineCautionStrong evidence

Berberine lowers blood sugar. Its effect in trials was comparable to some diabetes drugs. Combined, hypoglycemia is possible — monitor closely.

Niacin (Nicotinic Acid)CautionStrong evidence

High-dose niacin can raise blood sugar. Doses of 1.5 g/day or more are most likely to worsen insulin resistance and raise glucose. Monitor your blood sugar if you take it.

Note

CurcuminNoteMechanism-based

Curcumin may lower blood sugar. Possible additive effect with diabetes medication. Monitor glucose.

ChromiumNoteStrong evidence

Chromium may slightly lower blood sugar. Effects are small and inconsistent, but monitor glucose when starting.

Alpha-Lipoic AcidNoteHuman data

Alpha-lipoic acid may lower blood sugar. Monitor glucose when combining with insulin or sulfonylureas.

Panax GinsengNoteHuman data

Ginseng may lower blood sugar. Possible additive effect with diabetes medication.

GlucosamineNoteHuman data

Glucosamine may raise blood sugar in some people. NIH notes that glucosamine may increase blood glucose in some people. Check your readings for a few weeks after starting.

Black Seed OilNoteStrong evidence

Black seed may lower blood sugar. Meta-analyses report lower fasting glucose and HbA1c. Monitor your blood sugar when starting it.

Inositol (Myo-inositol)NoteStrong evidence

Inositol can improve insulin sensitivity. In trials it lowered fasting insulin and insulin resistance. Monitor your blood sugar if you take glucose-lowering medication.

Check your stack with Diabetes medication

Common questions

Can I take Ashwagandha with Diabetes medication?

Ashwagandha may lower blood sugar. Additive glucose-lowering could increase hypoglycemia risk with insulin or sulfonylureas. Monitor glucose.

Can I take Berberine with Diabetes medication?

Berberine lowers blood sugar. Its effect in trials was comparable to some diabetes drugs. Combined, hypoglycemia is possible — monitor closely.

Can I take Niacin (Nicotinic Acid) with Diabetes medication?

High-dose niacin can raise blood sugar. Doses of 1.5 g/day or more are most likely to worsen insulin resistance and raise glucose. Monitor your blood sugar if you take it.

Can I take Curcumin with Diabetes medication?

Curcumin may lower blood sugar. Possible additive effect with diabetes medication. Monitor glucose.

Can I take Chromium with Diabetes medication?

Chromium may slightly lower blood sugar. Effects are small and inconsistent, but monitor glucose when starting.

Can I take Alpha-Lipoic Acid with Diabetes medication?

Alpha-lipoic acid may lower blood sugar. Monitor glucose when combining with insulin or sulfonylureas.

Last reviewed Sourced from NIH fact sheets and peer-reviewed studies.How we make this contentReport an error