Piperine + Resveratrol

Can you take Piperine and Resveratrol together?

SynergyAnimal / lab only

Probably yes — though the evidence comes from mice.

What to do. Optional. Same drug-interaction caveat as piperine with curcumin.

Mechanism

Piperine may increase resveratrol exposure

In mice, co-administered piperine greatly increased peak resveratrol levels by slowing its glucuronidation. This has not been confirmed in humans.

Evidence: Animal / lab only — Evidence limited to animal or cell studies.

  1. 01Johnson JJ et al. Enhancing the bioavailability of resveratrol by combining it with piperine. Mol Nutr Food Res 2011 (mouse study).
  2. 02Walle T et al. High absorption but very low bioavailability of oral resveratrol in humans. Drug Metab Dispos 2004.

Timing

A day with Piperine and Resveratrol

  1. 08:00

    Breakfast

    with meal
  2. 12:30

    Lunch

    with meal

Taking more than these two?

Add the rest of your stack and your medications for a complete check.

Check my full stack

Buying guide

What to look for on the label

  • Piperine

    • Standardized 95% piperine, usually pre-combined with curcumin

  • Resveratrol

    • trans-Resveratrol
    • Micronized forms

Related

Other interactions

Curcumin + Piperine

Piperine increases curcumin bioavailability

Synergy→

NMN + Resveratrol

The NAD⁺ + sirtuin hypothesis

Synergy→

Nicotinamide Riboside (NR) + Resveratrol

The NAD⁺ + sirtuin hypothesis (NR version)

Synergy→

Learn more about Piperine and Resveratrol.